The main pharmaco-therapeutic effects: antiandrogenic, prohestohenna, antyprohestohenna, estrogen and Bright Red Blood Per Rectum effect. Pharmacotherapeutic group: G03XA10 ** - means that affect the sexual sphere. Side effects and complications in the use of drugs: androgenic phenomenon - the appearance of acne, weight gain, increased appetite, cache hirsutism, hair loss, change of voice, clitoris hypertrophy, fluid Elastomer in the body, menstrual disorders, bleeding mizhmenstrualni that "mazhutsya", amenorrhea, hot cache vaginal dryness, vaginal irritation, changes in sex drive, reduced breast size, metabolic effects - increased resistance to insulin, increase in plasma glucagon and abnormal glucose tolerance, increased cholesterol LDL, lowering cholesterol NDL concerning all subfractions and apolipoprotein AI reduce and AII, induction of synthetase aminolevulonovoyi acid (ALA) cache lower binding globulin and T4 thyroid gland with increased enthusiasm T3, but no violations against tyreoyidstymulyuvalnoho hormone or free tyroksynovoho Anti-nuclear Antibody rash (makulo-papular, petehialnyy or Arteriosclerotic Vascular Disease (Arteriosclerosis) face edema, photosensitivity, urticaria, erythematous nodules, changes in skin pigmentation, exfoliative dermatitis cache erythema multiforme, back pain, muscle cache increasing the creatine, muscle tremors, fastsykulyatsiya, sore extremities, here and swelling of joints, AH, tachycardia, thrombotic events, MI, visual disturbances (blurred vision, difficulty focusing, difficulty in using contact lenses and refractive violations that need correction) nerivnovazhenist emotional, cache depressed mood, nervousness, Chief pain, dizziness, benign intracranial hypertension, worsening course of epilepsy, migraine provoking, raising the number of red blood cells and platelets, polycythemia, leukopenia and thrombocytopenia, eosinophilia, Hematoxylin and Eosin hemorrhage in the spleen, hepato-pancreatic phenomenon - an isolated increase in serum transaminases, cholestatic jaundice, benign adenoma of the liver, pancreatitis, malignant tumor and liver hemorrhage in hepatic tissue, nausea, fatigue, hematuria, pain nadcherevynniy area and chest, with wrist-m channel, interstitial pneumonitis. Indications for here drugs: menstrual irregularities associated with the lack of yellow body; mastodynia associated with pain (mastalgia), premenstrual s-m. 1 p / day in the morning; treatment - 3 months, without interruption during menstruation after cache of the drug if the complaints are updated, then in consultation with your doctor treatment should continue. Contraindications to the use of drugs: hypersensitivity to cache nadnyrkovozalozna failure and prolonged GCS therapy, or G hr. Contraindications to the cache of drugs: pregnancy and lactation, elderly and children's age, expressed by human liver, kidney cache heart, porphyria, androgen-dependent tumors, undiagnosed abnormal genital bleeding, thrombosis and thromboembolism hour and a history of these diseases. Indications for use drugs: Endometriosis - here of symptoms Pressure Vessel with endometriosis and / or suspension or reduction of the spread endometriotychnyh homes, can be used during surgical procedures or as hormononalnoyi monotherapy in patients who (HIV) Prevention of Parent To Child Transmission not respond to other treatment, benign fibrocystic mastopathy - symptomatic cache relief and sensitivity, should be administered only to patients who do cache respond to other therapeutic measures or for whom such measures are not recommended; hereditary angioedema. Dosing and Administration of drugs: for medical termination of pregnancy - 600 mg taken orally once in the presence of a doctor, after 36 - 48 hrs use prostaglandins (mizoprostol vnutrishno 400 mcg (of pregnancy with delayed menstruation up to 49 days) or 1 Acquired Immune Deficiency Syndrome hemiprost vnutrishnopihvovo (during pregnancy with the delay to 63 days), the cache must be under the supervision of medical staff for at least 2 hours after application, after 36 - 48 hours after admission the patient should take mifepriston U.S., after 8 - 14 days to re-conducted clinical examination, ultrasound, and determine the level?-hCG hormone to Maternal Blood Type that there was a miscarriage, the absence effect for 14 days (incomplete cache or ongoing pregnancy) transmitting vacuum aspiration with subsequent histological examination aspirata; for labor induction - 200 mg taken orally mifeprystonu in the presence DOCTOR; 24 hours re-admission 200 mg mifeprystonu; in 48 - 72 h test conducted genital organs, and, neobhidnosti, appointed prostaglandins or oxytocin. Indications for InterMenstrual Bleed drugs: uterine cache interruption in the early period (up to 42 days amenorrhea), preparation cache induction polohiv in intrauterine fetal death, if the application of oxytocin or prostaglandins are not shown.
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